Publications
List of publications on Google Scholar: link
** Highlighted publications
Borys SM, Reilly SP, Magill I, Zemmour D, Brossay L. PD-1 Mediated Regulation of Unique Activated CD8 + T Cells by NK Cells in the Submandibular Gland. BioRxiv. 2023 Sep 17:2023.09.15.557930. Preprint. PMID: 37745414
Cecilia Larocca, Vignesh Shanmugam, David Zemmour, Joseph H Antin, Andrew A Lane. Shared Clonal Origin of Multiple Histiocytic and Dendritic Neoplasms and Polycythemia Vera, Follicular Lymphoma in 1 Patient. Am J Dermatopathol. 2022 May 30. PMID: 35642960
** David Zemmour, Ananda Goldrath, Mitchell Kronenberg, Joonsoo Kang, Christophe Benoist. The ImmGen consortium OpenSource T cell project. Nat Immunol 2022 May;23(5):643-644. PMID: 35469020
Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 Sep 22;6(18):e151981. PMID: 34403365
** Porritt RA*, Zemmour D*, Abe M* (*co-first authors), Lee Y, Meena Narayanan M, Teixeira de Carvalho T, Gomez AC, Martinon D, Santiskulvong C, Fishbein MC, Chen S, Crother TR, Shimada K, Arditi M, Noval Rivas M. Circ Res. 2021 Sep 14. Online ahead of print. PMID: 34517723
Juan Corchado-Garcia*, David Zemmour* (*co-first authors), Travis Hughes, Tudor Cristea-Platon, Patrick Lenehan, Colin Pawlowski, Sairam Bade, John C. O’Horo, Gregory J. Gores, Amy W. Williams, Andrew D. Badley, John Halamka, Abinash Virk, Melanie D. Swift, Tyler Wagner, Venky Soundararajan. Analysis of the Effectiveness of the Ad26.COV2.S Adenoviral Vector Vaccine for Preventing COVID-19. JAMA Netw Open. 2021;4(11):e2132540. doi:10.1001/jamanetworkopen.2021.32540
Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 Sep 22;6(18):e151981. doi: 10.1172/jci.insight.151981. PMID: 34403365
AJ Venkatakrishnan, Colin Pawlowski, David Zemmour, Travis Hughes, Akash Anand, Gabriela Berner, Nikhil Kayal, Arjun Puranik, Ian Conrad, Sairam Bade, Rakesh Barve, Purushottam Sinha, John C. O’Horo, Andrew D. Badley, Venky Soundararajan. Mapping each pre-existing condition’s association to short-term and long-term COVID-19 complications. NPJ Digit Med. 2021 Jul 27;4(1):117. doi: 10.1038/s41746-021-00484-7.
Deeksha Doddahonnaiah, Patrick Lenehan, Travis Hughes, David Zemmour, Enrique Garcia-Rivera, AJ Venkatakrishnan, Ramakrisha Chilaka, Apoorv Khare, Akash Anand, Rakesh Barve, Viswanathan Thiagarajan, Venky Soundararajan. A literature-derived knowledge graph augments the interpretation of single-cell RNA-seq datasets. Genes 2021, 12(6), 898; https://doi.org/10.3390/genes12060898
** David Zemmour, Louis-Marie Charbonnier, Juliette Leon, Emmanuelle Six, Sevgi Keles, Marianne Delville, Safa Baris, Julien Zuber, Karin Chen, Benedicte Neven, Maria I Garcia-Lloret, Franck Ruemmele, Carlo Brugnara, Nadine Cerf-Bensussan, Frederic Rieux-Laucat, Marina Cavazzana, Isabelle André, Talal A. Chatila, Diane Mathis, Christophe Benoist. Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations. Nat. Immunol. 2021 May;22(5):607-619. doi: 10.1038/s41590-021-00910-8. Epub 2021 Apr 8. PMID: 33833438
David Zemmour, Annette Kim. Angioimmunoblastic T cell lymphoma with RHOA mutation. Book Chapter in Molecular Hematopathology-An Integrated Case-Based Approach. 2021. Authors: Rose C Beck, Erika M Moore. ISBN: 978-0-89189-6814 (link)
AJ Venkatakrishnan, Arjun Puranik, Akash Anand, David Zemmour, Xiang Yao, Xiaoying Wu, Ramakrishna Chilaka, Dariusz K. Murakowski, Kristopher Standish, Bharathwaj Raghunathan, Tyler Wagner, Enrique Garcia-Rivera, Hugo Solomon, Abhinav Garg, Rakesh Barve, Anuli Anyanwu-Ofili, Najat Khan, Venky Soundararajan. Knowledge synthesis from 100 million biomedical documents augments the deep expression profiling of coronavirus receptors. Elife. 2020 May 28;9:e58040. doi: 10.7554/eLife.58040. PMID: 32463365
** Zemmour D*, Kiner E* (co-first author), Benoist C. CD4+ teff cell heterogeneity: the perspective from single-cell transcriptomics. Curr Opin Immunol. 2020 Apr;63:61-67. doi: 10.1016/j.coi.2020.02.004. Epub 2020 Apr 4. Review. PMID: 32259715
Wang K, Yaghi OK, Spallanzani RG, Chen X, Zemmour D, Lai N, Chiu IM, Benoist C, Mathis D. Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5402-5408. doi: 10.1073/pnas.1922559117. Epub 2020 Feb 26. PMID: 32102913
Zilionis R, Engblom C, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ, Klein AM. Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species. Immunity. 2019 May 21;50(5):1317-1334.e10. PMID: 30979687
Spallanzani RG, Zemmour D, Xiao T, Jayewickreme T, Li C, Bryce PJ, Benoist C, Mathis D. Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors. Sci Immunol. 2019 May 3;4(35). PMID: 31053654
** DiSpirito J*, Zemmour D* (co-first author), Zilionis R, Klein AM, Benoist C, Mathis D. The molecular and epigenomic underpinnings of tissue-Treg heterogeneity. Science immunology. 2018; 3(27). PMID: 30217811
Chaoran Li, Joanna DiSpirito, David Zemmour, Raul German Spallanzani, Wilson Kuswanto, Christophe Benoist and Diane Mathis. Tracking adipose-tissue Treg provenance, dependencies, and activities via T cell receptor transgenic mice. Cell. 2018; 174(2):285-299.e12. PMID: 29887374
** Zemmour D, Zilionis R, Kiner E, Klein AM, Mathis D, Benoist C.Single-cell gene expression reveals a landscape of Treg phenotypes shaped by the TCR. Nat Immunol. 2018 Mar;19(3):291-301. PMID: 29434354
C Engblom, C Pfirschke, R Zilionis, J da Silva Martins, S. A. Bos, Gabriel Courties, S Rickelt, N Severe, N Baryawno, J Faget, V Savova, D Zemmour, J Kline, M Siwicki, C Garris, F Pucci, H Liao, Y.J Lin, A Newton, O Yaghi, Y Iwamoto, B Tricot, G.R. Wojtkiewicz, M Nahrendorf, V Cortez-Retamozo, E Meylan, R O. Hynes, M Demay, A Klein, M. A. Bredella, D. T. Scadden, R Weissleder, M. J. Pittet. Osteoblasts remotely supply lung tumors with cancer-enhancing SiglecFhigh neutrophils. Science. 2017 Dec 1;358(6367). PMID: 29191879
Zemmour D, Pratama A, Loughhead SM, Mathis D, Benoist C. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3472-E3480. doi: 10.1073/pnas.1700946114. Epub 2017 Apr 10. PMID: 28396406
Zilionis R, Nainys J, Veres A, Savova V, Zemmour D, Klein AM, Mazutis L. Single-cell barcoding and sequencing using droplet microfluidics. Nat Protoc. 2017 Jan;12(1):44-73. doi: 10.1038/nprot.2016.154. Epub 2016 Dec 8. PMID: 27929523
Sefik E, Geva-Zatorsky N, Oh S, Konnikova L, Zemmour D, McGuire AM, Burzyn D, Ortiz-Lopez A, Lobera M, Yang J, Ghosh S, Earl A, Snapper SB, Jupp R, Kasper D, Mathis D, Benoist C. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory T cells. Science. August 2015 Volume 28 Issue 349, pp993-7. DOI: 10.1126/science.aaa9420
Meredith M, Zemmour D, Mathis D, Benoist C. Aire controls gene expression in the thymic epithelium with ordered stochasticity. Nat Immunol. Sep 2015, Volume 16, Issue 9, pp942-9. PMID: 26272906
Puyraimond-Zemmour D, Vignot S. The metabolism of cancer cells: the Warburg effect. Oncologie September 2013, Volume 15, Issue 9, pp 435-440. DOI 10.1007/s10269-013-2318-2
Shay T, Jojic V, Zuk O, Rothamel K, Puyraimond-Zemmour D, Feng T, Wakamatsu E, Benoist C, Koller D, Regev A. Conservation and divergence in the transcriptional programs of the human and mouse immune systems. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2946-51. PMID: 23382184
Suspène R, Petit V, Puyraimond-Zemmour D, Aynaud MM, Henry M, Gueétard D, Rusniok C, Wain-Hobson S, and Vartanian JP. Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles vaccines. Journal of Virology, March 2010 ; 85(5) p2458-2462 PMID: 21159878
Suspène R., Renard M., Henry M., Guétard D., Puyraimond-Zemmour D., Billecocq A., Bouloy M., Tangy F., Vartanian JP and Wain-Hobson S. Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs. Nucleic Acid Research, 2008 Jul; 36(12) PMID: 18515351